Blar i forfatter "Cavadino, Alana"

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    • Association of vitamin D status with arterial blood pressure and hypertension risk: A mendelian randomisation study 

      Vimaleswaran, Kerani S.; Cavadino, Alana; Berry, Diane J.; Jorde, Rolf; Grimnes, Guri; Dieffenbach, Aida Karina; Lu, Chen; Alves, Alexessander Couto; Heerspink, Hiddo J. Lambers; Tikkanen, Emmi; Eriksson, Joel; Wong, Andrew; Mangino, Massimo; Jablonski, Kathleen A.; Nolte, Ilja M.; Houston, Denise K.; Ahluwalia, Tarunveer Singh; van der Most, Peter J.; Pasko, Dorota; Zgaga, Lina; Thiering, Elisabeth; Schöttker, B; Saum, KU; Brenner, H; Järvelin, MR; Tzoulaki, I; Snieder, H; Stolk, RP; Hartman, CA; de Boer, RA; van der Harst, P; Navis, G; de Borst, MH; Lorentzon, M; Mellström, D; Ohlsson, C; Hardy, R; Kuh, D; Cooper, JA; Acharya, J; Humphries, SE; Hingorani, AD; Kumari, M; Kivimaki, M; Spector, TD; Kritchevsky, SB; Lohman, KK; Sørensen, TIA; Frayling, TM; Campbell, H; Theodoratou, E; Fraser, RM; Wilson, JF; Rudan, I; Price, JF; McLachlan, S; Vitart, V; Navarro, P; Huffman, JE; Hayward, C; Wright, AF; Tiesler, CMT; Heinrich, J; McCarthy, MI; Ingelsson, E; Arden, N; Cooper, C; Dupuis, J; Herzig, KH; Sebert, S; Pouta, A; Laitinen, J; Kleber, ME; März, W; Jameson, K; Osmond, C; Raitakari, O; Ripatti, S; Lahti, J; Eriksson, JG; Penninx, BW; Billings, LK; Florez, JC; Rejnmark, L; Langdahl, BL; Paternoster, L; Hernandez, DG; Byberg, L; Michaelsson, K; Hagström, E; Melhus, H; Ljunggren, O; Lind, L; Jula, A; Polasek, O; Salomaa, V; Karlsson, M; Bandinelli, S; Lehtimäki, T; Wang, TJ; Pilz, S; Whittaker, JC (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-06-25)
      Background Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian randomisation approach to test whether 25(OH)D concentration is causally associated with blood pressure and hypertension risk.<p> <p>Methods In this mendelian randomisation study, we generated ...

    • Vitamin D and cognitive function: A Mendelian randomisation study 

      Maddock, Jane; Zhou, Ang; Cavadino, Alana; Kuźma, Elżbieta; Bao, Yanchun; Smart, Melissa C.; Saum, Kai-Uwe; Schöttker, Ben; Engmann, Jorgen; Kjærgaard, Marie; Karhunen, Ville; Zhan, Yiqiang; Lehtimäki, Terho; Rovio, Suvi P.; Byberg, Liisa; Lahti, Jari; Marques-Vidal, Pedro; Sen, Abhijit; Perna, Laura; Schirmer, Henrik; Singh-Manoux, Archana; Auvinen, Juha; Hutri-Kähönen, Nina; Kähönen, Mika; Kilander, Lena; Räikkönen, Katri; Melhus, Håkan; Ingelsson, Erik; Guessous, Idris; Petrovic, Katja E.; Schmidt, Helena; Schmidt, Reinhold; Vollenweider, Peter; Lind, Lars; Eriksson, Johan G.; Michaëlsson, Karl; Raitakari, Olli T; Hägg, Sara; Pedersen, Nancy L.; Herzig, Karl-Heinz; Järvelin, Marjo-Riitta; Veijola, Juha; Kivimäki, Mika; Jorde, Rolf; Brenner, Hermann; Kumari, Meena; Power, Chris; Llewellyn, David J.; Hyppönen, Elina (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-16)
      The causal nature of the association between hypovitaminosis D and poor cognitive function in mid- to later-life is uncertain. Using a Mendelian randomisation(MR) approach, we examined the causal relationship between 25(OH)D and cognitive function. Data came from 172,349 participants from 17 cohorts. DHCR7(rs12785878), CYP2R1 rs12794714) and their combined synthesis score were chosen to proxy 25(OH)D. ...